P-513 Effect of embryo migration after embryo transfer with fresh oocyte donation cycles on pregnancy outcomes

Abstract Study question Is there any effect of embryo migration on clinical pregnancy rate and live birth in fresh oocyte donation cycles? Summary answer Clinical were not affected from direction. What is known already Embryo transfer the final crucial step to affect success rates up date has been vast amount studies optimize for better implantation increasing rate. Embryos are loaded catheter mostly order air-embryo-air-medium. By doing so, we indirectly visualize embryo(s) via air bubbles rely bubble position as a reflector position. In literature, no investigating whether after 60 minutes this outcomes. design, size, duration The study included (OD) cycles recipient women. vitro fertilization (IVF) cycles, frozen-thawed cryopreserved-thawed OD excluded. Participants/materials, setting, methods distance was assessed by ultrasound twice, one them immediately (ET) second at 60th ET. All embryos expulsed 10-20 mm fundus. first group consisted patients whose migrated towards fundus, with remained between 10 20 fundus third including cervix. Three groups compared Main results role chance A total 611 recruited study. At ET; 123 (20.1%) located nearer than (Group 1), 476 (77.9%) same initial zone 2) 12 (2%) moved more away fundal endometrium cervix 3). group1, 96 pregnancies (CPR:78.0%) 78 births (LBR: 63.4%). 2, CPR LBR 72.1% (n = 343) 66% 314), respectively. 3, 8 (CPR:66.7%) all had (LBR:66.7%). There significant difference terms groups. Limitations, reasons caution Our search impact high number patients. Although our population sufficient participants analyzing LBR; believe prospective designed required. Wider implications findings reveals that concept fact almost 20% migrate, or On other hand, stayed static migrated, LBRs freshOD independent possible migration. Trial registration NCT044855669